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ey0015.3-6 | Maternal thyroid disease during pregnancy | ESPEYB15

3.6 Maternal thyroid function and child educational attainment: prospective cohort study

SM Nelson , C Haig , A Mc Connachie , N Sattar , SM Ring , GD Smith , DA Lawlor , RS Lindsay

To read the full abstract: BMJ 2018;360:k452The role of thyroid hormones during early gestation is well established by animal studies. In humans, previous studies have shown that maternal hypothyroxinemia was associated with either an early reduction in psychomotor scales (e.g. Bayley scale of infant development) or later in late infancy or adolescence. However, randomized controlled trials on...

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ey0016.1-1 | (1) | ESPEYB16

1.1. Genome-wide association analyses of chronotype in 697, 828 individuals provides insights into circadian rhythms

SE Jones , JM Lane , AR Wood , VT van Hees , J Tyrrell , RN Beaumont , AR Jeffries , HS Dashti , M Hillsdon , KS Ruth , MA Tuke , H Yaghootkar , SA Sharp , Y Jie , WD Thompson , JW Harrison , A Dawes , EM Byrne , H Tiemeier , KV Allebrandt , J Bowden , DW Ray , RM Freathy , A Murray , DR Mazzotti , PR Gehrman , DA Lawlor , TM Frayling , MK Rutter , DA Hinds , R Saxena , MN Weedon

To read the full abstract: Nat Commun 2019;10:343This paper reports many loci associated with chronotype (i.e. being a morning person or evening person) in a genome-wide association study (GWAS) of 697, 828 participants from the UK Biobank and 23andMe cohorts. The link between chronotype and sleep timing and quality is well known. It was therefore interestin...

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ey0016.15-5 | (1) | ESPEYB16

15.5. Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

E Voerman , S Santos , B Patro Golab , P Amiano , F Ballester , H Barros , A Bergstrom , MA Charles , L Chatzi , C Chevrier , GP Chrousos , E Corpeleijn , N Costet , S Crozier , G Devereux , M Eggesbo , S Ekstrom , MP Fantini , S Farchi , F Forastiere , V Georgiu , KM Godfrey , D Gori , V Grote , W Hanke , I Hertz-Picciotto , B Heude , D Hryhorczuk , RC Huang , H Inskip , N Iszatt , AM Karvonen , LC Kenny , B Koletzko , LK Kupers , H Lagstrom , I Lehmann , P Magnus , R Majewska , J Makela , Y Manios , FM McAuliffe , SW McDonald , J Mehegan , M Mommers , CS Morgen , TA Mori , G Moschonis , D Murray , CN Chaoimh , EA Nohr , AM Nybo Andersen , E Oken , A Oostvogels , A Pac , E Papadopoulou , J Pekkanen , C Pizzi , K Polanska , D Porta , L Richiardi , SL Rifas-Shiman , L Ronfani , AC Santos , M Standl , C Stoltenberg , E Thiering , C Thijs , M Torrent , SC Tough , T Trnovec , S Turner , L van Rossem , A von Berg , M Vrijheid , TGM Vrijkotte , J West , A Wijga , J Wright , O Zvinchuk , TIA Sorensen , DA Lawlor , R Gaillard , VWV Jaddoe

To read the full abstract: PLoS Med, 2019;16:e1002744These investigators painstakingly collated individual-level data from 37 pregnancy and birth cohort studies from Europe, North America, and Australia, comprising 162,129 mothers and their children, in order to identify the optimal levels gestational weight gain in relation to risk of offspring obes...

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ESPE Yearbook of Paediatric Endocrinology

3.6 Maternal thyroid function and child educational attainment: prospective cohort study

1.1. Genome-wide association analyses of chronotype in 697, 828 individuals provides insights into circadian rhythms

15.5. Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

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